Single-cell transcriptomic analysis reveals tumor cell heterogeneity and immune microenvironment features of pituitary neuroendocrine tumors

Abstract Background Pituitary neuroendocrine tumors (PitNETs) are one of the most common types of intracranial tumors.Currently, the cellular characteristics of normal pituitary and various other types of PitNETs are still not completely understood.Methods We performed single-cell RNA sequencing (scRNA-seq) on 4 normal samples and 24 PitNET samples

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Revertant Mosaicism in Epidermolysis Bullosa

Epidermolysis bullosa (EB) is a group of genetic blistering diseases characterized by mechanically Roleplay fragile skin and mucocutaneous involvement.Historically, disease management has focused on supportive care.The development of new genetic, cellular, and recombinant protein therapies has shown promise, and this review summarizes a unique gene

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Enhancing Building Archaeology: Drawing, UAV Photogrammetry and Scan-to-BIM-to-VR Process of Ancient Roman Ruins

This research investigates the utilisation of the scan-to-HBIM-to-XR process and unmanned aerial vehicle (UAV) photogrammetry to improve the depiction of archaeological ruins, specifically focusing on Battery Tray the Claudius Anio Novus aqueduct in Tor Fiscale Park, Rome.UAV photogrammetry is vital in capturing detailed aerial imagery of the aqued

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